| Reaction Details |
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 | Report a problem with these data |
| Target | Aminopeptidase B |
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| Ligand | BDBM50022751 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_35352 |
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| Ki | 4.6±n/a nM |
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| Citation |  Ocain, TD; Rich, DH Synthesis of sulfur-containing analogues of bestatin. Inhibition of aminopeptidases by alpha-thiolbestatin analogues. J Med Chem31:2193-9 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminopeptidase B |
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| Name: | Aminopeptidase B |
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| Synonyms: | AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep |
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| Type: | PROTEIN |
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| Mol. Mass.: | 72609.93 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1344423 |
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| Residue: | 650 |
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| Sequence: | MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
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| BDBM50022751 |
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| n/a |
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| Name | BDBM50022751 |
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| Synonyms: | 2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-methyl-pentanoic acid: | CHEMBL1204264 | CHEMBL305198 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24N2O3S |
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| Mol. Mass. | 324.438 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O |
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| Structure | 
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