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TargetPhenylethanolamine N-methyltransferase
LigandBDBM13016
Substrate/Competitorn/a
Meas. Tech.ChEBML_152426
Ki 10300±n/a nM
Citation Grunewald, GLSall, DJMonn, JA Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines. J Med Chem31:433-44 (1988) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Phenylethanolamine N-methyltransferase
Name:Phenylethanolamine N-methyltransferase
Synonyms:Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase
Type:Enzyme
Mol. Mass.:30916.97
Organism:Bos taurus (bovine)
Description:n/a
Residue:283
Sequence:
MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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  Blast E-value cutoff:
BDBM13016
n/a
NameBDBM13016
Synonyms:1,2,3,4-tetrahydroisoquinoline | CHEMBL14346 | THIQ 6 | tetrahydroisoquinoline
TypeSmall organic molecule
Emp. Form.C9H11N
Mol. Mass.133.1903
SMILESC1Cc2ccccc2CN1
Structure
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