| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50018730 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_148991 |
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| Ki | 0.230000±n/a nM |
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| Citation |  Zimmerman, DM; Cantrell, BE; Swartzendruber, JK; Jones, ND; Mendelsohn, LG; Leander, JD; Nickander, RC Synthesis and analgesic properties of N-substituted trans-4a-aryldecahydroisoquinolines. J Med Chem31:555-60 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44503.11 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
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| Residue: | 398 |
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| Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50018730 |
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| n/a |
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| Name | BDBM50018730 |
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| Synonyms: | 3-(2-Phenethyl-octahydro-isoquinolin-4a-yl)-phenol | CHEMBL359363 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29NO |
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| Mol. Mass. | 335.4825 |
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| SMILES | Oc1cccc(c1)C12CCCC[C@H]1CN(CCc1ccccc1)CC2 |
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| Structure | 
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