| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50022017 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196299 |
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| IC50 | 240±n/a nM |
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| Citation |  Hui, KY; Holtzman, EJ; Quinones, MA; Hollenberg, NK; Haber, E Design of rat renin inhibitory peptides. J Med Chem31:1679-86 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | RENI_RAT | Ren | Ren1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44272.67 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_222765 |
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| Residue: | 402 |
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| Sequence: | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
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| BDBM50022017 |
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| n/a |
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| Name | BDBM50022017 |
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| Synonyms: | CHEMBL414537 | Pro-His-Pro-Phe-His-Statine-Leu-Phe-NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C54H75N13O9 |
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| Mol. Mass. | 1050.255 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CCCN1)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
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| Structure | 
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