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TargetAdenosylhomocysteinase
LigandBDBM50011180
Substrate/Competitorn/a
Meas. Tech.ChEBML_197366
IC50 230000±n/a nM
Citation Borcherding DRNarayanan SHasobe MMcKee JGKeller BTBorchardt RT Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 11. Molecular dissections of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem 31:1729-38 (1988) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosylhomocysteinase
Name:Adenosylhomocysteinase
Synonyms:Adenosylhomocysteinase | AdoHcyase | CUBP | Liver copper-binding protein | S-adenosyl-L-homocysteine hydrolase
Type:PROTEIN
Mol. Mass.:47687.65
Organism:Mus musculus
Description:ChEMBL_196559
Residue:432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVET
AVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHF
KDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMP
INGPFKPDHYRY
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  Blast E-value cutoff:
BDBM50011180
n/a
NameBDBM50011180
Synonyms:4-(6-Amino-purin-9-yl)-but-2-en-1-ol | CHEMBL49917
TypeSmall organic molecule
Emp. Form.C9H11N5O
Mol. Mass.205.2165
SMILESNc1ncnc2n(C\C=C\CO)cnc12
Structure
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