| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50367906 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29632 (CHEMBL639739) |
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| Ki | 7.7±n/a nM |
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| Citation |  Trivedi, BK; Bruns, RF C2,N6-disubstituted adenosines: synthesis and structure-activity relationships. J Med Chem32:1667-73 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50367906 |
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| n/a |
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| Name | BDBM50367906 |
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| Synonyms: | CHEMBL603995 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N6O4 |
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| Mol. Mass. | 452.5062 |
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| SMILES | OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC3CC4CCC3C4)nc(Nc3ccccc3)nc12 |r,TLB:14:15:21:19.18| |
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| Structure | 
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