| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50017237 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201290 |
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| Ki | 231±n/a nM |
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| Citation |  Hutchison, AJ; de Jesus, R; Williams, M; Simke, JP; Neale, RF; Jackson, RH; Ambrose, F; Barbaz, BJ; Sills, MA Benzofuro[2,3-c]pyridin-6-ols: synthesis, affinity for opioid-receptor subtypes, and antinociceptive activity. J Med Chem32:2221-6 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25246.51 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | O55242 |
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| Residue: | 223 |
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| Sequence: | MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPS
TLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
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| BDBM50017237 |
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| n/a |
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| Name | BDBM50017237 |
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| Synonyms: | (4aS,9aR)-4a-Ethyl-2-propyl-1,2,3,4,4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridin-6-ol | CHEMBL304616 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H23NO2 |
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| Mol. Mass. | 261.3593 |
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| SMILES | CCCN1CC[C@]2(CC)[C@H](C1)Oc1ccc(O)cc21 |
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| Structure | 
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