| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50017232 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_201290 |
|---|
| Ki | 2.3±n/a nM |
|---|
| Citation |  Hutchison, AJ; de Jesus, R; Williams, M; Simke, JP; Neale, RF; Jackson, RH; Ambrose, F; Barbaz, BJ; Sills, MA Benzofuro[2,3-c]pyridin-6-ols: synthesis, affinity for opioid-receptor subtypes, and antinociceptive activity. J Med Chem32:2221-6 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25246.51 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | O55242 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPS
TLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
|
|
|
|---|
| BDBM50017232 |
|---|
| n/a |
|---|
| Name | BDBM50017232 |
|---|
| Synonyms: | 3-Cyclopropylmethyl-5-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one | CHEMBL71301 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H25NO2 |
|---|
| Mol. Mass. | 299.4073 |
|---|
| SMILES | CCC1CN(CC2CC2)C2C(C)C1c1cc(O)ccc1C2=O |TLB:11:10:20.13.19:4.2.3| |
|---|
| Structure | 
|
|---|
Search and Browse
