Reaction Details |
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Target | Chymotrypsinogen A |
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Ligand | BDBM50014578 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_216617 |
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Ki | 60±n/a nM |
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Citation | Angelastro, MR; Mehdi, S; Burkhart, JP; Peet, NP; Bey, P Alpha-diketone and alpha-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases. J Med Chem33:11-3 (1990) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Chymotrypsinogen A |
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Name: | Chymotrypsinogen A |
Synonyms: | Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin) |
Type: | Serine protease |
Mol. Mass.: | 25670.88 |
Organism: | Bos taurus (bovine) |
Description: | n/a |
Residue: | 245 |
Sequence: | CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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BDBM50014578 |
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n/a |
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Name | BDBM50014578 |
Synonyms: | 3-(2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-2-oxo-4-phenyl-butyric acid methyl ester | CHEMBL282374 |
Type | Small organic molecule |
Emp. Form. | C24H28N2O6 |
Mol. Mass. | 440.4889 |
SMILES | COC(=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C |
Structure |
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