Reaction Details |
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Target | Sex hormone-binding globulin |
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Ligand | BDBM50367916 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_35818 |
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IC50 | 3.7±n/a nM |
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Citation | Winneker, RC; Wagner, MM; Singh, B A novel, nonsteroidal inhibitor of androgen binding to the rat androgen binding protein: diethyl [[[3-(2,6-dimethyl-4-pyridinyl)-4-fluorophenyl]amino]methylene] propanedioate. J Med Chem33:129-32 (1990) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Sex hormone-binding globulin |
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Name: | Sex hormone-binding globulin |
Synonyms: | ABP | SBP | SHBG_RAT | Sex hormone-binding globulin | Sex steroid-binding protein | Shbg | Testis-specific androgen-binding protein |
Type: | PROTEIN |
Mol. Mass.: | 44530.46 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_35819 |
Residue: | 403 |
Sequence: | MEKGEVASLRCRLLLLLLLLTLPPTHQGRTLRHIDPIQSAQDSPAKYLSNGPGQEPVTVL
TIDLTKISKPSSSFEFRTWDPEGVIFYGDTNTEDDWFMLGLRDGQLEIQLHNLWARLTVG
FGPRLNDGRWHPVELKMNGDSLLLWVDGKEMLCLRQVSASLADHPQLSMRIALGGLLLPT
SKLRFPLVPALDGCIRRDIWLGHQAQLSTSARTSLGNCDVDLQPGLFFPPGTHAEFSLQD
IPQPHTDPWTFSLELGFKLVDGAGRLLTLGTGTNSSWLTLHLQDQTVVLSSEAEPKLALP
LAVGLPLQLKLDVFKVALSQGPKMEVLSTSLLRLASLWRLWSHPQGHLSLGALPGEDSSA
SFCLSDLWVQGQRLDIDKALSRSQDIWTHSCPQSPSNDTHTSH
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BDBM50367916 |
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n/a |
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Name | BDBM50367916 |
Synonyms: | METHYLTRIENOLONE | Metribolone | R-1881 |
Type | Small organic molecule |
Emp. Form. | C19H24O2 |
Mol. Mass. | 284.3927 |
SMILES | C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C |r,c:16,19,t:9| |
Structure |
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