| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50367920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_208196 (CHEMBL819099) |
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| Ki | 54000±n/a nM |
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| Citation |  Palomino, E; Meltsner, BR; Kessel, D; Horwitz, JP Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. J Med Chem33:258-63 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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| BDBM50367920 |
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| n/a |
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| Name | BDBM50367920 |
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| Synonyms: | CHEMBL1790742 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13N5O3S |
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| Mol. Mass. | 283.307 |
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| SMILES | Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=S |
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| Structure | 
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