Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM50000492 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_3470 | ||
Ki | 0.700000±n/a nM | ||
Citation | Rizzi, JP; Nagel, AA; Rosen, T; McLean, S; Seeger, T An initial three-component pharmacophore for specific serotonin-3 receptor ligands. J Med Chem33:2721-5 (1990) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
Type: | Protein | ||
Mol. Mass.: | 55283.27 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P46098 | ||
Residue: | 478 | ||
Sequence: |
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BDBM50000492 | |||
n/a | |||
Name | BDBM50000492 | ||
Synonyms: | (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride) | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride) | CHEMBL18041 | HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide | ZACOPRIDE | ZACOPRIDE,R | ZACOPRIDE,RS | ZACOPRIDE,S | ||
Type | Small organic molecule | ||
Emp. Form. | C15H20ClN3O2 | ||
Mol. Mass. | 309.791 | ||
SMILES | COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| | ||
Structure |