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TargetKappa-type opioid receptor
LigandBDBM50013955
Substrate/Competitorn/a
Meas. Tech.ChEMBL_146232
Ki 1618±n/a nM
Citation de Costa BRRice KCBowen WDThurkauf ARothman RBBand LJacobson AERadesca LContreras PCGray NM Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity sigma receptor ligands. Identification of a new class of highly potent and selective sigma receptor probes. J Med Chem 33:3100-10 (1990) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Kappa-type opioid receptor
Name:Kappa-type opioid receptor
Synonyms:Kappa Opioid Receptor | OPIATE Kappa | Opiate Kappa 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42744.99
Organism:Cavia porcellus (domestic guinea pig)
Description:P41144
Residue:380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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  Blast E-value cutoff:
BDBM50013955
n/a
NameBDBM50013955
Synonyms:N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide | N-methyl-2-(naphthalen-2-yl)-N-[(2S)-2-(pyrrolidin-1-yl)cyclohexyl]acetamide
TypeSmall organic molecule
Emp. Form.C23H30N2O
Mol. Mass.350.4971
SMILESCN(C1CCCC[C@@H]1N1CCCC1)C(=O)Cc1ccc2ccccc2c1
Structure
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