| Reaction Details |
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 | Report a problem with these data |
| Target | Atrial natriuretic peptide receptor 3 |
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| Ligand | BDBM50013343 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_35004 |
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| IC50 | 0.220000±n/a nM |
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| Citation |  DiMaio, J; Jaramillo, J; Wernic, D; Grenier, L; Welchner, E; Adams, J Synthesis and biological activity of atrial natriuretic factor analogues: effect of modifications to the disulfide bridge. J Med Chem33:661-7 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Atrial natriuretic peptide receptor 3 |
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| Name: | Atrial natriuretic peptide receptor 3 |
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| Synonyms: | ANP-C | ANPR-C | ANPRC | ANPRC_MOUSE | Atrial natriuretic peptide C-type receptor | Atrial natriuretic peptide clearance receptor | Atrial natriuretic peptide receptor 3 | Atrial natriuretic peptide receptor C | EF-2 | NPR-C | Npr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59812.13 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_35004 |
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| Residue: | 536 |
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| Sequence: | MRSLLLFTFSACVLLARVLLAGGASSGAGDTRPGSRRRAREALAAQKIEVLVLLPRDDSY
LFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARG
AKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMG
EMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNFDETKDLDLD
DIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIELFNSSSYGDGSWRRG
DKHDSEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEGFHDAI
LLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVVAMTDTE
AGTQEVIGDYFGKEGRFQMRSNVKYPWGPLKLRLDETRIVEHTNSSPCKSSGGLEESAVT
GIVVGALLGAGLLMAFYFFRKKYRITIERRNQQEESNIGKHRELREDSIRSHFSVA
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| BDBM50013343 |
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| n/a |
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| Name | BDBM50013343 |
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| Synonyms: | CHEMBL3349621 | deamino [Mpr105,Cys121] r-ANF (99-126)(Atrial Natriuretic Factor) |
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| Type | Small organic molecule |
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| Emp. Form. | C101H154N32O30S2 |
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| Mol. Mass. | 2360.63 |
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| SMILES | [H][C@]1([#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)[C@@]([H])([#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6]-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6]1=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](-[#8])=O)[#6@@H](-[#6])-[#6]-[#6])[#6@@H](-[#6])-[#6]-[#6] |
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| Structure | 
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