| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50013620 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146439 (CHEMBL757336) |
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| Ki | 11±n/a nM |
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| Citation |  Portoghese, PS; Sultana, M; Takemori, AE Design of peptidomimetic delta opioid receptor antagonists using the message-address concept. J Med Chem33:1714-20 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50013620 |
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| n/a |
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| Name | BDBM50013620 |
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| Synonyms: | 2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-3-mercapto-3-methyl-butyrylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-3-mercapto-3-methyl-butyric acid (DPLPE) | CHEMBL2372782 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H41N5O7S2 |
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| Mol. Mass. | 647.806 |
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| SMILES | CC(C)(S)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)(C)S)C(O)=O |
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| Structure | 
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