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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50013764 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_146692 | ||
| IC50 | 1±n/a nM | ||
| Citation |  Klein, P; Nelson, WL; Yao, YH; Simon, EJ Electrophilic alpha-methylene-gamma-lactone and isothiocyanate opioid ligands related to etorphine. J Med Chem33:2286-96 (1990) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 45038.37 | ||
| Organism: | CALF | ||
| Description: | OPIATE Mu 2 0 CALF::P79350 | ||
| Residue: | 401 | ||
| Sequence: |
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| BDBM50013764 | |||
| n/a | |||
| Name | BDBM50013764 | ||
| Synonyms: | 5-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11,18-tetraen-16-yl)-3-methylenetetrahydro-2-furanone | CHEMBL3038199 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H31NO5 | ||
| Mol. Mass. | 461.5494 | ||
| SMILES | [H][C@@]1(CC(=C)C(=O)O1)[C@@]1([H])C[C@]23C=C[C@]1(OC)[C@]1([H])Oc4c5c(C[C@@]2([H])N(CC2CC2)CC[C@@]315)ccc4O |wU:33.36,8.9,17.19,wD:11.12,14.16,1.0,24.27,c:13,TLB:27:26:11:21.22.23,(12.43,-15.69,;12.44,-13.82,;13.68,-14.75,;13.19,-16.2,;14.29,-17.29,;11.67,-16.18,;10.88,-17.51,;11.21,-14.72,;12.46,-12.28,;14.06,-13.23,;13.8,-11.53,;13.82,-10.01,;12.44,-9.99,;12.44,-11.35,;11.14,-11.5,;9.8,-12.25,;8.48,-11.46,;11.16,-9.97,;9.66,-10.31,;10.41,-8.48,;11.16,-6.94,;12.51,-7.7,;13.84,-6.94,;15.17,-7.71,;15.15,-9.25,;15.55,-10.74,;16.48,-10.02,;17.81,-10.79,;19.14,-10.02,;20.68,-10.02,;19.54,-8.52,;16.23,-8.13,;13.59,-8.13,;12.49,-9.22,;13.84,-5.39,;12.49,-4.62,;11.16,-5.4,;9.83,-4.62,)| | ||
| Structure | 
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