| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50205990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_215037 (CHEMBL881616) |
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| Ki | 61±n/a nM |
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| Citation |  Bock, MG; DiPardo, RM; Williams, PD; Pettibone, DJ; Clineschmidt, BV; Ball, RG; Veber, DF; Freidinger, RM Receptor ligands which bind the oxytocin receptor with selectivity and high affinity. Chemical modification of a Streptomyces silvensis derived cyclic hexapeptide. J Med Chem33:2321-3 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40761.85 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | n/a |
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| Residue: | 371 |
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| Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
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| BDBM50205990 |
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| n/a |
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| Name | BDBM50205990 |
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| Synonyms: | CHEMBL395429 | OXYTOCIN |
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| Type | Small organic molecule |
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| Emp. Form. | C43H66N12O12S2 |
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| Mol. Mass. | 1007.187 |
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| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O |r| |
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| Structure | 
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