| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1) dopamine receptor |
|---|
| Ligand | BDBM82247 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_31418 |
|---|
| Ki | 1.3±n/a nM |
|---|
| Citation |  Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands. J Med Chem34:2946-53 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1) dopamine receptor |
|---|
| Name: | D(1) dopamine receptor |
|---|
| Synonyms: | D(1) dopamine receptor | DRD1_CARAU | Dopamine D1 receptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 40664.04 |
|---|
| Organism: | Carassius auratus |
|---|
| Description: | n/a |
|---|
| Residue: | 363 |
|---|
| Sequence: | MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVT
NFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISV
DRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRR
DLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQ
IRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTS
NGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSL
NKN
|
|
|
|---|
| BDBM82247 |
|---|
| n/a |
|---|
| Name | BDBM82247 |
|---|
| Synonyms: | 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390) | CAS_87134-87-0 | CHEMBL2158641 | CHEMBL62 | SCH 23388 | SCH 23390 | SCH 23390 (R-enantiomer) | SCH 23390,R(+) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18ClNO |
|---|
| Mol. Mass. | 287.784 |
|---|
| SMILES | CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
