| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
|---|
| Ligand | BDBM50368151 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_138980 |
|---|
| Ki | 13±n/a nM |
|---|
| Citation |  Triggle, DJ; Kwon, YW; Abraham, P; Pitner, JB; Mascarella, SW; Carroll, FI Synthesis, molecular modeling studies, and muscarinic receptor activity of azaprophen analogues. J Med Chem34:3164-71 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M3 |
|---|
| Name: | Muscarinic acetylcholine receptor M3 |
|---|
| Synonyms: | ACM3_RAT | Cholinergic, muscarinic M3 | Chrm-3 | Chrm3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 66086.66 |
|---|
| Organism: | RAT |
|---|
| Description: | Cholinergic, muscarinic M3 CHRM3 RAT::P08483 |
|---|
| Residue: | 589 |
|---|
| Sequence: | MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSNDTSSDPLG
GHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVIS
MNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRT
TKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFY
MPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGVK
RSSRRKYGRCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSET
RAIYSIVLKLPGHSSILNSTKLPSSDNLQVSNEDLGTVDVERNAHKLQAQKSMGDGDNCQ
KDFTKLPIQLESAVDTGKTSDTNSSADKTTATLPLSFKEATLAKRFALKTRSQITKRKRM
SLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNP
VCYALCNKTFRTTFKTLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
|
|
|
|---|
| BDBM50368151 |
|---|
| n/a |
|---|
| Name | BDBM50368151 |
|---|
| Synonyms: | CHEMBL322582 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H31NO2 |
|---|
| Mol. Mass. | 425.5619 |
|---|
| SMILES | CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1 |TLB:4:5:11.19:8,THB:12:11:8:10.5.6| |
|---|
| Structure | 
|
|---|
Search and Browse
