| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50010292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_59152 |
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| Ki | 0.660000±n/a nM |
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| Citation |  Bakthavachalam, V; Baindur, N; Madras, BK; Neumeyer, JL Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands. J Med Chem34:3235-41 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50010292 |
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| n/a |
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| Name | BDBM50010292 |
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| Synonyms: | 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-{2-[4-(7-nitro-benzo[1,2,5]oxadiazol-4-ylamino)-phenyl]-ethyl}-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL92649 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H36FN7O5 |
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| Mol. Mass. | 677.724 |
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| SMILES | [O-][N+](=O)c1ccc(Nc2ccc(CCN3CN(c4ccccc4)C4(CCN(CCCC(=O)c5ccc(F)cc5)CC4)C3=O)cc2)c2[n-][o+]nc12 |
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| Structure | 
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