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TargetGag-Pol polyprotein [489-587]
LigandBDBM519
Substrate/Competitorn/a
Meas. Tech.ChEMBL_160733 (CHEMBL767111)
Ki 0.120000±n/a nM
Citation Krohn, ARedshaw, SRitchie, JCGraves, BJHatada, MH Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere. J Med Chem34:3340-2 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM519
n/a
NameBDBM519
Synonyms:(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide | CHEMBL114 | Fortovase | Invirase | Ro 31-8959 | SQV | Saquinavir
TypeSmall organic molecule
Emp. Form.C38H50N6O5
Mol. Mass.670.8408
SMILESCC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1 |@:16|
Structure
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