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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50010496
Substrate/Competitorn/a
Meas. Tech.ChEMBL_160732
IC50>100±n/a nM
Citation Krohn ARedshaw SRitchie JCGraves BJHatada MH Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere. J Med Chem 34:3340-2 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50010496
n/a
NameBDBM50010496
Synonyms:Benzyloxycarbonyl-Asn-Phe-[R]-[CH(OH)CH2N]-decahydroisoquinolin-3-yl-carbonyloxy-Ile-Val-OMe | CHEMBL324206
TypeSmall organic molecule
Emp. Form.C44H64N6O9
Mol. Mass.821.0138
SMILESCC[C@H](C)[C@H](NC(=O)C1CC2CCCCC2CN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)OC
Structure
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