| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50010494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_160731 (CHEMBL767110) |
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| IC50 | >100±n/a nM |
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| Citation |  Krohn, A; Redshaw, S; Ritchie, JC; Graves, BJ; Hatada, MH Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere. J Med Chem34:3340-2 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50010494 |
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| n/a |
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| Name | BDBM50010494 |
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| Synonyms: | CHEMBL3350205 | N*1*-[1-Benzyl-3-(3-tert-butylcarbamoyl-octahydro-isoquinolin-2-yl)-2-hydroxy-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C38H50N6O5 |
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| Mol. Mass. | 670.8408 |
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| SMILES | CC(C)(C)NC(=O)[C@@H]1CC2CCCCC2CN1C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1 |
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| Structure | 
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