| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50368168 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_196878 (CHEMBL883536) |
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| Ki | 9700±n/a nM |
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| Citation |  Jarvi, ET; McCarthy, JR; Mehdi, S; Matthews, DP; Edwards, ML; Prakash, NJ; Bowlin, TL; Sunkara, PS; Bey, P 4',5'-unsaturated 5'-halogenated nucleosides. Mechanism-based and competitive inhibitors of S-adenosyl-L-homocysteine hydrolase. J Med Chem34:647-56 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | Adenosylhomocysteinase | Ahcy | SAHH_RAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47537.52 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1507790 |
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| Residue: | 432 |
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| Sequence: | MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVET
AVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHF
KDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMP
INGPFKPDHYRY
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| BDBM50368168 |
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| n/a |
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| Name | BDBM50368168 |
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| Synonyms: | CHEMBL609353 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H11F2N5O3 |
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| Mol. Mass. | 287.2228 |
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| SMILES | Nc1ncnc2n(cnc12)C1O[C@H](C(F)F)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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