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TargetGag-Pol polyprotein [489-587]
LigandBDBM50000758
Substrate/Competitorn/a
Meas. Tech.ChEMBL_159122 (CHEMBL878774)
Ki 7±n/a nM
Citation Thaisrivongs, STomasselli, AGMoon, JBHui, JMcQuade, TJTurner, SRStrohbach, JWHowe, WJTarpley, WGHeinrikson, RL Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activity. J Med Chem34:2344-56 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50000758
n/a
NameBDBM50000758
Synonyms:CHEMBL48770
TypeSmall organic molecule
Emp. Form.C43H59N7O7
Mol. Mass.785.9713
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)[C@@H](O)[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)COc1cccc2ccccc12)C(=O)NCc1ccccn1
Structure
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