| Reaction Details |
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 | Report a problem with these data |
| Target | Cytidine deaminase |
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| Ligand | BDBM50007155 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_52540 |
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| Ki | 1600000±n/a nM |
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| Citation |  Lin, TS; Luo, MZ; Liu, MC; Clarke-Katzenburg, RH; Cheng, YC; Prusoff, WH; Mancini, WR; Birnbaum, GI; Gabe, EJ; Giziewicz, J Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride. J Med Chem34:2607-15 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cytidine deaminase |
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| Name: | Cytidine deaminase |
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| Synonyms: | CDA | CDD | CDD_HUMAN | Cytidine deaminase | Cytidine deaminase (CDA) |
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| Type: | Ezyme |
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| Mol. Mass.: | 16185.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32320 |
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| Residue: | 146 |
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| Sequence: | MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACY
PLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKP
DGTYIVMTVQELLPSSFGPEDLQKTQ
|
|
|
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| BDBM50007155 |
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| n/a |
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| Name | BDBM50007155 |
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| Synonyms: | 4-Amino-1-(3-hydroxy-5-hydroxymethyl-4-methylene-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one | CHEMBL88675 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13N3O4 |
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| Mol. Mass. | 239.2279 |
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| SMILES | Nc1ccn(C2OC(CO)C(=C)C2O)c(=O)n1 |
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| Structure | 
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