| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thermolysin |
|---|
| Ligand | BDBM50006112 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_210389 |
|---|
| Ki | 21300±n/a nM |
|---|
| Citation |  Bohacek, RS; McMartin, C Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design. J Med Chem35:1671-84 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thermolysin |
|---|
| Name: | Thermolysin |
|---|
| Synonyms: | THER_BACTH | npr |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60097.54 |
|---|
| Organism: | Bacillus thermoproteolyticus |
|---|
| Description: | ChEMBL_1468794 |
|---|
| Residue: | 548 |
|---|
| Sequence: | MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEEL
VYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDG
TLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVY
VNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVG
VGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDA
PAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQ
TFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEI
GEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGG
THYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQ
AFDAVGVK
|
|
|
|---|
| BDBM50006112 |
|---|
| n/a |
|---|
| Name | BDBM50006112 |
|---|
| Synonyms: | ((S)-1-Carbamoyl-3-methyl-butyl)-phosphoramidic acid | (P-Leu-NH2) (1-Carbamoyl-3-methyl-butyl)-phosphoramidic acid | CHEMBL47541 | N~2~-phosphono-L-leucinamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H15N2O4P |
|---|
| Mol. Mass. | 210.1681 |
|---|
| SMILES | CC(C)C[C@H](NP(O)(O)=O)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
