| Reaction Details |
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 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
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| Ligand | BDBM50368379 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210761 |
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| Ki | 494000±n/a nM |
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| Citation |  Cheng, L; Goodwin, CA; Schully, MF; Kakkar, VV; Claeson, G Synthesis and biological activity of ketomethylene pseudopeptide analogues as thrombin inhibitors. J Med Chem35:3364-9 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Urokinase-type plasminogen activator |
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| Name: | Urokinase-type plasminogen activator |
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| Synonyms: | 3.4.21.73 | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator chain B | Urokinase-type plasminogen activator long chain A | Urokinase-type plasminogen activator short chain A | Urokinase-type plasminogen activator/surface receptor | uPA |
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| Type: | Enzyme |
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| Mol. Mass.: | 48528.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00749 |
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| Residue: | 431 |
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| Sequence: | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL
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| BDBM50368379 |
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| n/a |
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| Name | BDBM50368379 |
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| Synonyms: | CHEMBL1202120 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H47N7O4 |
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| Mol. Mass. | 617.7815 |
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| SMILES | [#7]-[#6@H](-[#6](-c1ccccc1)-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 |r| |
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| Structure | 
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