Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50004787 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_159302 (CHEMBL769355) |
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IC50 | 7000±n/a nM |
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Citation | DeCamp, DL; Babé, LM; Salto, R; Lucich, JL; Koo, MS; Kahl, SB; Craik, CS Specific inhibition of HIV-1 protease by boronated porphyrins. J Med Chem35:3426-8 (1992) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50004787 |
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n/a |
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Name | BDBM50004787 |
Synonyms: | CHEMBL442513 | Porphyrin analogue |
Type | Small organic molecule |
Emp. Form. | C70H74N8O12 |
Mol. Mass. | 1219.383 |
SMILES | CN(C)c1ccc(cc1)C(=O)OCC(OC(=O)c1ccc(cc1)N(C)C)c1c(C)c2cc3[nH]c(cc4nc(cc5nc(cc1[nH]2)c(C)c5CCC(O)=O)c(CCC(O)=O)c4C)c(C)c3C(COC(=O)c1ccc(cc1)N(C)C)OC(=O)c1ccc(cc1)N(C)C |
Structure |
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