| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pol polyprotein |
|---|
| Ligand | BDBM50004783 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_159124 |
|---|
| IC50 | 1550±n/a nM |
|---|
| Citation |  DeCamp, DL; Babé, LM; Salto, R; Lucich, JL; Koo, MS; Kahl, SB; Craik, CS Specific inhibition of HIV-1 protease by boronated porphyrins. J Med Chem35:3426-8 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pol polyprotein |
|---|
| Name: | Pol polyprotein |
|---|
| Synonyms: | Human immunodeficiency virus type 2 pol protein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 100453.78 |
|---|
| Organism: | Human immunodeficiency virus 2 |
|---|
| Description: | ChEMBL_159124 |
|---|
| Residue: | 876 |
|---|
| Sequence: | MTGDTPINIFGRNILTALGMSLNLPVARIEPIKITLKPGKDGPRLKQWPLTKEKVEALKE
ICEKMEKEGQLEEAPPTNPYNTPTFAIKKKDKNKWRMLIDFRELNRVTQDFTEIQLGIPH
PAGLAKKKRITVLDVGDAYFSIPLYEDFRPYTAFTLPSVNNVEPGKRYIYKVLPQGWKGS
PAIFQYTMRQILEPFRKANPDVILIQYMDDILIASDRTGLEHDKVVLQLKELLNGLGFST
PEEKFQKDPPFQWMGYELWPTKWKLQKIQLPQKETWTVNDIQKLVGILNWAAQIYPGIKT
KHLCRLIRGKMTLTEEVQWTELAEAELEENRIILDQEQEGHYYQEEKELEATIQKSQDNQ
WTYKIHQEEKILKVGKYAKIKNTHTNGVRLLAQVVQKIGKEALVIWGRIPKFHLPVERET
WEQWWDNYWQVTWIPEWDFVSTPPLVRLTFNLVGDPIPGTETFYTDGSCNRQSKEGKAGY
VTDRGRDKVRVLEQTTNQQAELEAFAMALADSGPKVNIIVDSQYVMGIVASQPTESESRI
VNQIIEDMIKKEAVYVAWIPAHKGIGGNQEVDHLVSQGIRQVLFLEKIEPAQEEHEKYHS
NIKELIHKFGIPQLVARQIVNTCAQCQQKGEAIHGQVNAEIGVWQMDCTHLEGKIIIVAV
HVASGFIEAEVIPQESGRQTALFLLKLASRWPITHLHTDNGPNFTSQEVKMVAWWVGIEQ
SFGVPYNPQSQGVVEAMNHHLKNQISRIREQANTVETIVLMAVHCMNFKRRGGIGDMTPA
ERLINMITTEQEIQFLQRKNSNFKKFQVYYREGRDQLWKGPGELLWKGEGAVIVKVGADI
KVVPRRKAKIIRDYGGRQELDSSPHLEGAREDGEVA
|
|
|
|---|
| BDBM50004783 |
|---|
| n/a |
|---|
| Name | BDBM50004783 |
|---|
| Synonyms: | 3-[18-(2-Carboxy-ethyl)-8,13-bis-(1,2-diacetoxy-ethyl)-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl]-propionic acid | CHEMBL408667 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C54H54N4O12 |
|---|
| Mol. Mass. | 951.0262 |
|---|
| SMILES | Cc1c(CCC(O)=O)c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(C)c5C(COC(=O)C1=CCC1)OC(=O)C1=CCC1)c(C)c4C(COC(=O)C1=CCC1)OC(=O)C1=CCC1)c(C)c3CCC(O)=O |t:35,43,57,65| |
|---|
| Structure | 
|
|---|
Search and Browse
