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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50368409
Substrate/Competitorn/a
Meas. Tech.ChEBML_157563
Ki 0.500000±n/a nM
Citation Rich DHPrasad JVSun CQGreen JMueller RHouseman KMacKenzie DMalkovsky M New hydroxyethylamine HIV protease inhibitors that suppress viral replication. J Med Chem 35:3803-12 (1992) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50368409
n/a
NameBDBM50368409
Synonyms:CHEMBL1790877 | CHEMBL3349488
TypeSmall organic molecule
Emp. Form.C49H57N7O8
Mol. Mass.872.019
SMILES[H][C@@](O)(CN1CCCC1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)OC)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1
Structure
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