Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50001713 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_146240 | ||
IC50 | 0.750000±n/a nM | ||
Citation | Klein, P; Nelson, WL O3-(2-carbomethoxyallyl) ethers of opioid ligands derived from oxymorphone, naltrexone, etorphine, diprenorphine, norbinaltorphimine, and naltrindole. Unexpected O3-dealkylation in the opioid radioligand displacement assay. J Med Chem35:4589-94 (1993) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 11165.58 | ||
Organism: | GUINEA PIG | ||
Description: | P97266 | ||
Residue: | 98 | ||
Sequence: |
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BDBM50001713 | |||
n/a | |||
Name | BDBM50001713 | ||
Synonyms: | CHEMBL143815 | methyl 2-[19-(1-hydroxy-1-methylbutyl)-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10,16-tetraen-11-yloxymethyl]acrylate | ||
Type | Small organic molecule | ||
Emp. Form. | C30H39NO6 | ||
Mol. Mass. | 509.6338 | ||
SMILES | CCC[C@@](C)(O)[C@H]1C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4OCC(=C)C(=O)OC |wU:3.2,20.22,wD:25.29,14.15,8.8,6.5,11.12,3.4,c:9,(9.11,-3.65,;7.57,-3.65,;6.8,-2.32,;5.26,-2.32,;5.23,-.78,;5.65,-3.81,;3.72,-2.32,;2.95,-.99,;1.41,-.96,;1.41,-2.5,;2.92,-2.11,;2.92,-3.65,;3.69,-5,;5.23,-5,;1.38,-3.65,;-.18,-4.02,;-1.65,-3.62,;-.88,-2.29,;-1.65,-.96,;-.9,.37,;.64,.37,;1.03,1.86,;1.97,3.07,;-.3,1.09,;-.72,-1.52,;.64,-2.29,;-3.19,-.96,;-3.96,-2.29,;-3.19,-3.62,;-3.96,-4.95,;-5.5,-4.95,;-6.27,-6.31,;-5.5,-7.64,;-7.81,-6.31,;-8.58,-7.64,;-8.58,-4.95,;-7.81,-3.62,)| | ||
Structure |