Reaction Details | |||
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Target | Kappa-type opioid receptor | ||
Ligand | BDBM50123599 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_145206 | ||
IC50 | 3.4±n/a nM | ||
Citation | Klein, P; Nelson, WL O3-(2-carbomethoxyallyl) ethers of opioid ligands derived from oxymorphone, naltrexone, etorphine, diprenorphine, norbinaltorphimine, and naltrindole. Unexpected O3-dealkylation in the opioid radioligand displacement assay. J Med Chem35:4589-94 (1993) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Kappa-type opioid receptor | |||
Name: | Kappa-type opioid receptor | ||
Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 42744.99 | ||
Organism: | Cavia porcellus (domestic guinea pig) | ||
Description: | P41144 | ||
Residue: | 380 | ||
Sequence: |
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BDBM50123599 | |||
n/a | |||
Name | BDBM50123599 | ||
Synonyms: | ETORPHINE | ||
Type | Small organic molecule | ||
Emp. Form. | C25H33NO4 | ||
Mol. Mass. | 411.5338 | ||
SMILES | [H][C@@]1(C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4O)[C@](C)(O)CCC |r,wU:15.17,20.21,25.33,1.0,wD:9.10,3.3,6.7,c:4,THB:17:16:13.12.14:3,(12.5,-39.62,;11.02,-39.23,;12.37,-38.48,;12.38,-36.94,;11.6,-38.27,;10.46,-37.1,;9.7,-38.44,;8.61,-39.53,;7.12,-39.12,;9.72,-36.9,;8.94,-35.56,;9.73,-33.87,;11.06,-34.63,;12.4,-33.87,;13.73,-34.64,;13.72,-36.18,;14.48,-34.84,;15.81,-34.06,;12.94,-34.84,;12.54,-35.75,;11.06,-36.16,;12.39,-32.32,;11.06,-31.55,;9.73,-32.32,;8.39,-31.55,;11,-40.77,;10.98,-42.3,;9.46,-40.75,;12.54,-40.79,;13.29,-42.14,;14.83,-42.16,)| | ||
Structure |