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TargetAdenosine receptor A1
LigandBDBM50008388
Substrate/Competitorn/a
Meas. Tech.ChEBML_29305
Ki 0.230000±n/a nM
Citation Jacobson, KAvan Galen, PJWilliams, M Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. J Med Chem35:407-22 (1992) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:Protein
Mol. Mass.:36704.13
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50008388
n/a
NameBDBM50008388
Synonyms:3-[2-(4-Amino-3-iodo-phenyl)-ethyl]-8-cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione | CHEMBL334776
TypeSmall organic molecule
Emp. Form.C21H26IN5O2
Mol. Mass.507.3679
SMILESCCCn1c(=O)n(CCc2ccc(N)c(I)c2)c2nc([nH]c2c1=O)C1CCCC1
Structure
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