| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50005497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_138559 (CHEMBL745515) |
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| IC50 | 630±n/a nM |
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| Citation |  Sowell, JW; Tang, Y; Valli, MJ; Chapman, JM; Usher, LA; Vaughan, CM; Kosh, JW Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine. J Med Chem35:1102-8 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_MOUSE | Cholinergic receptor, muscarinic 1, CNS | Cholinergic, muscarinic | Chrm-1 | Chrm1 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51400.50 |
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| Organism: | Mus musculus |
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| Description: | Cholinergic, muscarinic 0 0::Q52KQ0 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50005497 |
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| n/a |
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| Name | BDBM50005497 |
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| Synonyms: | CHEMBL12937 | {5-[4-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-butylsulfanylmethyl]-furan-2-ylmethyl}-dimethyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H32N2O2S2 |
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| Mol. Mass. | 396.61 |
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| SMILES | CN(C)Cc1ccc(CSCCCCSCc2ccc(CN(C)C)o2)o1 |
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| Structure | 
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