| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
|---|
| Ligand | BDBM50005503 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_139893 (CHEMBL744480) |
|---|
| IC50 | 1400±n/a nM |
|---|
| Citation |  Sowell, JW; Tang, Y; Valli, MJ; Chapman, JM; Usher, LA; Vaughan, CM; Kosh, JW Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine. J Med Chem35:1102-8 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M2 |
|---|
| Name: | Muscarinic acetylcholine receptor M2 |
|---|
| Synonyms: | ACM2_MOUSE | Chrm-2 | Chrm2 | Muscarinic acetylcholine receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 51515.43 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_139897 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGGTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDDNSRQTCIKIVTKTQKGDACTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
|
|
|---|
| BDBM50005503 |
|---|
| n/a |
|---|
| Name | BDBM50005503 |
|---|
| Synonyms: | CHEMBL13308 | {5-[2-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethylsulfanylmethyl]-furan-2-ylmethyl}-dimethyl-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H28N2O2S2 |
|---|
| Mol. Mass. | 368.557 |
|---|
| SMILES | CN(C)Cc1ccc(CSCCSCc2ccc(CN(C)C)o2)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
