| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50006092 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_221704 |
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| IC50 | 130±n/a nM |
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| Citation |  Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem35:1650-62 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50006092 |
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| n/a |
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| Name | BDBM50006092 |
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| Synonyms: | 3-{3-[(2,6-Di-tert-butyl-4-dodecyloxy-phenoxy)-hydroxy-phosphoryloxy]-benzyl}-thiazol-3-ium | CHEMBL45182 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H54NO5PS |
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| Mol. Mass. | 643.856 |
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| SMILES | CCCCCCCCCCCCOc1cc(c(OP([O-])(=O)Oc2cccc(C[n+]3ccsc3)c2)c(c1)C(C)(C)C)C(C)(C)C |
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| Structure | 
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