| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50046118 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_48094 |
|---|
| Ki | 39±n/a nM |
|---|
| Citation |  Corringer, PJ; Weng, JH; Ducos, B; Durieux, C; Boudeau, P; Bohme, A; Roques, BP CCK-B agonist or antagonist activities of structurally hindered and peptidase-resistant Boc-CCK4 derivatives. J Med Chem36:166-72 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | CCK-2 receptor | CCK-B receptor | CCK-BR | CCKBR | CCKRB | Cholecystokinin A | Cholecystokinin receptor | Cholecystokinin-2 Receptor | GASR_HUMAN | Gastrin/cholecystokinin type B receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 48445.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Stable expression of human CCK-2 receptors in HEK 293 cells. |
|---|
| Residue: | 447 |
|---|
| Sequence: | MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
PDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50046118 |
|---|
| n/a |
|---|
| Name | BDBM50046118 |
|---|
| Synonyms: | CHEMBL3351057 | N-{[1-tert-Butoxycarbonyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-phenyl-methyl}-3-(2-dimethylamino-3-naphthalen-1-yl-propionylamino)-succinamic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C42H47N5O7 |
|---|
| Mol. Mass. | 733.8519 |
|---|
| SMILES | CN(C)[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC(C)(C)C)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
