Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAdenosine receptor A1
LigandBDBM50004583
Substrate/Competitorn/a
Meas. Tech.ChEBML_29637
Ki 0.750000±n/a nM
Citation Suzuki, FShimada, JShiozaki, SIchikawa, SIshii, ANakamura, JNonaka, HKobayashi, HFuse, E Adenosine A1 antagonists. 3. Structure-activity relationships on amelioration against scopolamine- or N6-((R)-phenylisopropyl)adenosine-induced cognitive disturbance. J Med Chem36:2508-18 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:Protein
Mol. Mass.:36704.13
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004583
n/a
NameBDBM50004583
Synonyms:8-(Octahydro-pentalen-2-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | CHEMBL84144
TypeSmall organic molecule
Emp. Form.C19H28N4O2
Mol. Mass.344.4512
SMILESCCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CC2CCCC2C1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: