| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50004734 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_101219 |
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| Ki | 40±n/a nM |
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| Citation |  Trybulski, EJ; Zhang, J; Kramss, RH; Mangano, RM The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives. J Med Chem36:3533-41 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50004734 |
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| n/a |
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| Name | BDBM50004734 |
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| Synonyms: | CHEMBL310852 | N-Methyl-N-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)-acetamide | N-Methyl-N-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)-acetamide (BM 5) | N-Methyl-N-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)-acetamide (R) | N-Methyl-N-(1-methyl-4-pyrrolidin-1-yl-but-2-ynyl)-acetamide (S) |
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| Type | Small organic molecule |
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| Emp. Form. | C12H20N2O |
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| Mol. Mass. | 208.3 |
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| SMILES | CC(C#CCN1CCCC1)N(C)C(C)=O |
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| Structure | 
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