| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50042586 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_99764 |
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| Ki | 6700000±n/a nM |
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| Citation |  Ding, CZ; Silverman, RB Transformation of heterocyclic reversible monoamine oxidase-B inactivators into irreversible inactivators by N-methylation. J Med Chem36:3606-10 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58428.94 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1501478 |
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| Residue: | 520 |
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| Sequence: | MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
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| BDBM50042586 |
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| n/a |
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| Name | BDBM50042586 |
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| Synonyms: | 4-Aminomethyl-1-(4-methoxy-phenyl)-pyrrolidin-2-one | CHEMBL120829 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16N2O2 |
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| Mol. Mass. | 220.2676 |
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| SMILES | COc1ccc(cc1)N1CC(CN)CC1=O |
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| Structure | 
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