| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50042998 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_30208 |
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| Ki | 5500±n/a nM |
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| Citation |  Chen, GT; King, M; Gusovsky, F; Creveling, CR; Daly, JW; Chen, BH; Nie, JY; Kirk, KL Syntheses of 2,5- and 2,6-difluoronorepinephrine, 2,5-difluoroepinephrine, and 2,6-difluorophenylephrine: effect of disubstitution with fluorine on adrenergic activity. J Med Chem36:3947-55 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46896.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_38603 |
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| Residue: | 418 |
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| Sequence: | MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQ
AIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRF
HAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRA
NLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNG
RTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
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| BDBM50042998 |
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| n/a |
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| Name | BDBM50042998 |
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| Synonyms: | 5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol(5-FNE) | CHEMBL129190 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H10FNO3 |
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| Mol. Mass. | 187.1683 |
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| SMILES | NCC(O)c1cc(O)c(O)c(F)c1 |
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| Structure | 
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