| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50047725 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_226569 (CHEMBL848647) |
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| Ki | 3.6±n/a nM |
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| Citation |  He, XS; Bowen, WD; Lee, KS; Williams, W; Weinberger, DR; de Costa, BR Synthesis and binding characteristics of potential SPECT imaging agents for sigma-1 and sigma-2 binding sites. J Med Chem36:566-71 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50047725 |
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| n/a |
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| Name | BDBM50047725 |
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| Synonyms: | (3-Iodo-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-amine | CHEMBL356909 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21IN2 |
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| Mol. Mass. | 344.2344 |
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| SMILES | CN(CCN1CCCC1)Cc1cccc(I)c1 |
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| Structure | 
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