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TargetAdenosylhomocysteinase
LigandBDBM50051436
Substrate/Competitorn/a
Meas. Tech.ChEMBL_197370
Ki 39±n/a nM
Citation Liu SWnuk SFYuan CRobins MJBorchardt RT Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase. J Med Chem 36:883-7 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosylhomocysteinase
Name:Adenosylhomocysteinase
Synonyms:Adenosylhomocysteinase
Type:PROTEIN
Mol. Mass.:47537.52
Organism:Rattus norvegicus
Description:ChEMBL_1507790
Residue:432
Sequence:
MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVET
AVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHF
KDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMP
INGPFKPDHYRY
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  Blast E-value cutoff:
BDBM50051436
n/a
NameBDBM50051436
Synonyms:(2R,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carbaldehyde | 5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carbaldehyde | CHEMBL77518
TypeSmall organic molecule
Emp. Form.C10H11N5O4
Mol. Mass.265.2254
SMILESNc1ncnc2n(cnc12)[C@@H]1O[C@@H](C=O)[C@@H](O)[C@H]1O
Structure
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