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TargetAdenosylhomocysteinase
LigandBDBM50046748
Substrate/Competitorn/a
Meas. Tech.ChEMBL_197370
Ki 40±n/a nM
Citation Liu SWnuk SFYuan CRobins MJBorchardt RT Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase. J Med Chem 36:883-7 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosylhomocysteinase
Name:Adenosylhomocysteinase
Synonyms:Adenosylhomocysteinase
Type:PROTEIN
Mol. Mass.:47537.52
Organism:Rattus norvegicus
Description:ChEMBL_1507790
Residue:432
Sequence:
MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVET
AVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHF
KDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMP
INGPFKPDHYRY
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  Blast E-value cutoff:
BDBM50046748
n/a
NameBDBM50046748
Synonyms:2-(6-Amino-purin-9-yl)-5-fluoromethylene-tetrahydro-furan-3,4-diol | CHEMBL171369
TypeSmall organic molecule
Emp. Form.C10H10FN5O3
Mol. Mass.267.2165
SMILESNc1ncnc2n(cnc12)[C@@H]1O\C(=C\F)[C@H](O)[C@@H]1O
Structure
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