| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM50046900 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_47253 (CHEMBL656659) |
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| IC50 | 18000±n/a nM |
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| Citation |  McConnell, RM; York, JL; Frizzell, D; Ezell, C Inhibition studies of some serine and thiol proteinases by new leupeptin analogues. J Med Chem36:1084-9 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | BCSB | CATB_BOVIN | CTSB | Cathepsin B precursor | Cathepsin B1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 36657.87 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Bovine spleen CB was purchased from Sigma Co. (USA). |
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| Residue: | 335 |
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| Sequence: | MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSW
NTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY
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| BDBM50046900 |
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| n/a |
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| Name | BDBM50046900 |
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| Synonyms: | 2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid (5-amino-1-formyl-pentyl)-amide | CHEMBL2373052 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H36N4O4 |
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| Mol. Mass. | 432.5563 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCCN)C=O |r| |
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| Structure | 
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