| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50038424 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_145747 (CHEMBL752636) |
|---|
| EC50 | 0.360000±n/a nM |
|---|
| Citation |  Qian, X; Kövér, KE; Shenderovich, MD; Lou, BS; Misicka, A; Zalewska, T; Horváth, R; Davis, P; Bilsky, EJ; Porreca, F Newly discovered stereochemical requirements in the side-chain conformation of delta opioid agonists for recognizing opioid delta receptors. J Med Chem37:1746-57 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40577.25 |
|---|
| Organism: | MOUSE |
|---|
| Description: | P32300 |
|---|
| Residue: | 372 |
|---|
| Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50038424 |
|---|
| n/a |
|---|
| Name | BDBM50038424 |
|---|
| Synonyms: | (S)-3-[(S)-2-((R)-2-Amino-propionylamino)-3-phenyl-propionylamino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid | CHEMBL49581 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H43N7O8 |
|---|
| Mol. Mass. | 605.6831 |
|---|
| SMILES | CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)N)C(C)C)C(=O)NCC(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
