| Reaction Details |
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 | Report a problem with these data |
| Target | Thermolysin |
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| Ligand | BDBM50038623 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_210390 (CHEMBL812110) |
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| IC50 | 4000±n/a nM |
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| Citation |  Gomez-Monterrey, I; Beaumont, A; Nemecek, P; Roques, BP; Fournie-Zaluski, MC New thiol inhibitors of neutral endopeptidase EC 3.4.24.11: synthesis and enzyme active-site recognition. J Med Chem37:1865-73 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thermolysin |
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| Name: | Thermolysin |
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| Synonyms: | THER_BACTH | npr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60097.54 |
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| Organism: | Bacillus thermoproteolyticus |
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| Description: | ChEMBL_1468794 |
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| Residue: | 548 |
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| Sequence: | MKMKMKLASFGLAAGLAAQVFLPYNALASTEHVTWNQQFQTPQFISGDLLKVNGTSPEEL
VYQYVEKNENKFKFHENAKDTLQLKEKKNDNLGFTFMRFQQTYKGIPVFGAVVTSHVKDG
TLTALSGTLIPNLDTKGSLKSGKKLSEKQARDIAEKDLVANVTKEVPEYEQGKDTEFVVY
VNGDEASLAYVVNLNFLTPEPGNWLYIIDAVDGKILNKFNQLDAAKPGDVKSITGTSTVG
VGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTLPGSLWADADNQFFASYDA
PAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAIRSSVHYSQGYNNAFWNGSQMVYGDGDGQ
TFIPLSGGIDVVAHELTHAVTDYTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEI
GEDVYTPGISGDSLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGG
THYGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTSQEVASVKQ
AFDAVGVK
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| BDBM50038623 |
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| n/a |
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| Name | BDBM50038623 |
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| Synonyms: | 2-(2-Benzyl-3-mercapto-5-methyl-hexanoylamino)-propionic acid | CHEMBL55286 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25NO3S |
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| Mol. Mass. | 323.45 |
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| SMILES | CC(C)CC(S)C(Cc1ccccc1)C(=O)NC(C)C(O)=O |
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| Structure | 
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