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TargetMu-type opioid receptor
LigandBDBM50029051
Substrate/Competitorn/a
Meas. Tech.ChEMBL_138892 (CHEMBL747884)
Ki 14000±n/a nM
Citation Zuckermann, RN; Martin, EJ; Spellmeyer, DC; Stauber, GB; Shoemaker, KR; Kerr, JM; Figliozzi, GM; Goff, DA; Siani, MA; Simon, RJ Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library. J Med Chem37:2678-85 (1994) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44503.11
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50029051
n/a
NameBDBM50029051
Synonyms:(-)-arterenol | (-)-noradrenaline | (-)-norepinephrine | (R)-(-)-norepinephrine | (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol | (R)-noradrenaline | (R)-norepinephrine | 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | CHEMBL1437 | NOREPINEPHRINE
TypeSmall organic molecule
Emp. Form.C8H11NO3
Mol. Mass.169.1778
SMILESNC[C@H](O)c1ccc(O)c(O)c1 |r|
Structure
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