Ki Summary

Reaction Details

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Target

Carnitine O-palmitoyltransferase 1, muscle isoform

Ligand

BDBM50037262

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_46319 (CHEMBL660720)

1400000±n/a nM

Citation

Saeed, A; McMillin, JB; Wolkowicz, PE; Brouillette, WJ 3-Amino-5,5-dimethylhexanoic acid. Synthesis, resolution, and effects on carnitine acyltransferases. J Med Chem37:3247-51 (1994) [PubMed]

More Info.:

Get all data from this article, Assay Method

Carnitine O-palmitoyltransferase 1, muscle isoform

Name:

Carnitine O-palmitoyltransferase 1, muscle isoform

Synonyms:

CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b

Type:

PROTEIN

Mol. Mass.:

88241.28

Organism:

Rattus norvegicus

Description:

ChEMBL_887447

Residue:

772

Sequence:

MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATG
IFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPS
VPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEE
YVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALG
MVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDL
EMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVA
LDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPI
IGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCL
YIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGY
GVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS

BDBM50037262

n/a

Name

BDBM50037262

Synonyms:

(R)-3-Hydroxy-5,5-dimethyl-hexanoic acid anion

Type

Small organic molecule

Emp. Form.

C8H15O3

Mol. Mass.

159.2034

SMILES

CC(C)(C)C[C@@H](O)CC([O-])=O

Structure